Hyperbaric Oxygen Therapy for Peripheral Neuropathy Due to Paclitaxel Analogs

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-60
SponsorGuangdong Provincial People's Hospital

About this trial

The goal of this study was to explore the safety and efficacy of hyperbaric oxygen in the treatment of peripheral neuropathy due to paclitaxel analogues

Eligibility criteria

Qualifiers

Patients with newly diagnosed breast cancer by pathology

Age 18-60 years

ECOG 0-2

CIPN patients with NCI-CTCAE grade 1 or higher after treatment with paclitaxel-based drugs

Disqualifiers

Patients with contraindications to hyperbaric oxygen i. Untreated pneumothorax. ii. concomitant administration of disulfiram. iii. concomitant administration of antineoplastic drugs such as bleomycin, cisplatin, adriamycin. iv. premature and/or low body mass newborns.

Other cancers

Trial design

Treatments tested in this trial

  • hyperbaric oxygenation treatment
  • routine care

Treatment groups

226 Participants
are divided into 2 treatment groups