Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked Pain

ConditionsHyperthermia Chronic Primary Pain Widespread Pain Muscular Disease Rheumatic Diseases Musculoskeletal Diseases Neuromuscular Disease Fibromyalgia Circadian Rhythm Body Temperature Changes Somatosensory Function Quantitative Sensory Testing Healthy

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-70

SponsorBern University of Applied Sciences

About this trial

This study, in a quasi-experimental matched two-group pre-post design, investigates the effect of serial water-filtered whole-body hyperthermia on circadian core body temperature, the somatosensory system (nociception) and the movement evoked pain in healthy and patients with chronic primary pain (e.g., fibromyalgia). The intervention lasts 3 weeks with two treatment sessions per week.

Eligibility criteria

Qualifiers

Confirmed diagnosis of widespread pain (ICD-11 MG30.01)

Widespread Pain Index (WPI) ≥ 7 and Symptom Severity (SS) scale ≥ 5 or WPI) ≥ 3 and SS ≥ 9,

Pain >= 3 month and VAS >= 4,0

Body - infrared-A-Bulb Distance < 38cm (overweight participants)

Disqualifiers

Participation in other clinical studies

Contraindications for hyperthermia (severe cardiovascular diseases, tumour diseases, acute infections, pregnant and breastfeeding women)

Acute and / or feverish microbial infections

Participants with severe somatic, rheumatic concomitant endocrine or neurological diseases, in particular neurological diseases associated with cognitive disorders, severe liver or kidney and cardiac diseases

Trial design

Treatments tested in this trial

serial whole body hyperthermia

Treatment groups

60 Participants

are divided into 1 treatment group

Sponsors and collaborators

Bern University of Applied Sciences

Lead sponsor

Dr. med. h.c Erwin Braun Stiftung

Collaborator

Source ClinicalTrials.gov