About this trial
The goal of this clinical trial is to learn if hypofractionated radiotherapy works to shorten the treatment time without increasing the side effects in patients of thymic epithelial tumors. The main questions it aims to answer are:
* Does Hypofractionated radiotherapy provide better results? * Can hypofractionated radiotherapy reduce toxic and side effects compared with conventional radiotherapy? Researchers will compare the efficacy and safety of hypofractionated radiotherapy after thymic tumor surgery.
Participants will:
* Receive hypofractionated radiotherapy or conventional radiotherapy * Visit the hospital regularly once every 12 weeks for checkups and tests
Eligibility criteria
Qualifiers
Patients must provide written informed consent.
18 years old ≤ age <75 years old.
Thymoma confirmed by pathology: type A, type AB, type B1, type B2, type B3. Thymic carcinoma. Patients with previous thymectomy were required to have complete surgical related data.
Masaoka⁃Koga ⁃ stage Ⅰ-Ⅲ
Disqualifiers
patients with prior thoracic radiotherapy;
diseases not suitable for radiotherapy, such as recent myocardial infarction, active congestive heart failure;
Uncontrolled infectious disease or other serious medical or mental illness that may interfere with care
Patients with other malignant tumors that are not under stable control;
Trial design
Treatments tested in this trial
- Hypofractionated Radiation Therapy
Treatment groups
Sponsors and collaborators
Rongrong Zhou
Lead sponsor
Xiangya Hospital of Central South University
Sponsor institution