Hypofractionated Radiotherapy Plus Temozolamide in Patients Younger Than 70 Years With Glioblastoma

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorHospital do Coracao

About this trial

The goal of this clinical trial is to evaluate the feasibility, safety and effectiveness of radiotherapy with fewer days of treatment and a higher dose of radiation each day in patients under 70 years of age diagnosed with a brain tumor known as glioblastoma.

Eligibility criteria

Qualifiers

Initial histological diagnosis of glioblastoma

Age > 18 and < 70 years;

Karnofsky Performance Status > 70%;

Patient consent to participate in the study.

Disqualifiers

Patients submitted to any type of previous radiotherapy in the cranial region;

Multicentric tumors;

Contraindication to chemotherapy with temozolomide;

Contraindications for performing magnetic resonance imaging (MRI), such as the use of implants or metallic prostheses;

Trial design

Treatments tested in this trial

  • Hypofractionated Radiation Therapy

Treatment groups

10 Participants
are divided into 1 treatment group

Locations

This trial has no locations

Sponsors and collaborators