About this trial
This study aim to implement intraoperative hemodynamic monitoring and management guided with HPI algorithm in frail patients undergoing elective abdominal surgery. Investigators hypothesize that the use of this algorithm will alter treatment of hypotension and reduces the amount of hypotension as measured by the time weighted average (TWA) during non-cardiac surgery and to anticipate a reduction of postoperative AKI incidents, to explore the clinical benefits of impact of Acumen guided algorithm hemodynamic management in postoperative intestinal function recovery, and postoperative cardiac complications.
Eligibility criteria
Qualifiers
Age> 60 years old
Frail score > 2
ASA≥2
Planned to receive general anesthesia
Disqualifiers
Severe cardiac arrhythmia including atrial fibrillation
Severe aortic stenosis
Uncontrolled Hypertension (sitting systolic blood pressure ≥ 160 mmHg and/or diastolic blood pressure ≥100 mmHg during screening)
Significant hypotension before surgery defined as a MAP <65mmHg
Trial design
Treatments tested in this trial
- HPI guided hemodynamic management
- standard arterial line