Hypotension Prediction Index and Intraoperative Hypotension Incidence

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60+
SponsorFirst Affiliated Hospital Xi'an Jiaotong University

About this trial

This study aim to implement intraoperative hemodynamic monitoring and management guided with HPI algorithm in frail patients undergoing elective abdominal surgery. Investigators hypothesize that the use of this algorithm will alter treatment of hypotension and reduces the amount of hypotension as measured by the time weighted average (TWA) during non-cardiac surgery and to anticipate a reduction of postoperative AKI incidents, to explore the clinical benefits of impact of Acumen guided algorithm hemodynamic management in postoperative intestinal function recovery, and postoperative cardiac complications.

Eligibility criteria

Qualifiers

Age> 60 years old

Frail score > 2

ASA≥2

Planned to receive general anesthesia

Disqualifiers

Severe cardiac arrhythmia including atrial fibrillation

Severe aortic stenosis

Uncontrolled Hypertension (sitting systolic blood pressure ≥ 160 mmHg and/or diastolic blood pressure ≥100 mmHg during screening)

Significant hypotension before surgery defined as a MAP <65mmHg

Trial design

Treatments tested in this trial

  • HPI guided hemodynamic management
  • standard arterial line

Treatment groups

100 Participants
are divided into 2 treatment groups