Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) for Perioperative Hemodynamic Optimization in Patients Under General Anesthesia

ConditionIntraoperative Hypotension

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorNational and Kapodistrian University of Athens

About this trial

This study investigates if the Hypotension Prediction Index (HPI) combined with the Assisted Fluid Management (AFM) software can improve perioperative hemodynamic management in adult patients undergoing general anesthesia. The main question is :

Does the HPI and AFM software reduce the incidence and duration of intraoperative hypotension? Does the HPI and AFM software optimize fluid and vasopressor administration? Does the HPI and AFM software improve perioperative outcomes? Participants will be randomly allocated to either an experimental group receiving goal directed hemodynamic therapy guided by HPI and AFM or a control group receiving conventional hemodynamic management.

Eligibility criteria

Qualifiers

Age > 18 years

Intraoperative monitoring > 2 hours or general anesthesia > 2 hours

Invasive arterial pressure monitoring

Target MAP ≥ 65 mm Hg intraoperatively

Disqualifiers

Target MAP other than 65 mm Hg

Severe preoperative hypotension (MAP < 65 mm Hg)

Severe heart failure (e.g. LVEF < 20%)

Emergency surgery

Trial design

Treatments tested in this trial

Acumen IQ sensor with Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) software
Conventional Intraoperative Hemodynamic management

Treatment groups

100 Participants

are divided into 2 treatment groups

Sponsors and collaborators

National and Kapodistrian University of Athens

Lead sponsor

Attikon Hospital

Sponsor institution

Attikon Hospital

Collaborator

Source ClinicalTrials.gov