Hypothyroidism After the TAVI Procedure in Elderly Patients

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age70+
SponsorUniversitair Ziekenhuis Brussel

About this trial

Aortic stenosis is highly prevalent in advancing age. The prognosis of this disease has dramatically changed with the surgical replacement of the aortic valve and the trans catheter aortic valve re-placement (TAVI). The TAVI procedure is also successful in octogenarians and frail patients. However, the evaluation before the TAVI procedure requires a high dosage of iodinated contrast agent with, consequently, an increased risk for thyroid dysfunction. The primary endpoint of this study is to assess, prospectively, the incidence and the predictive factors (underlying thyroid disease, medication, food preservative, topical antiseptics) of hypothyroidism after a TAVI procedure. The secondary endpoint is the influence of the occurrence of hypothyroidism after the TAVI procedure on the geriatric assessment.

Eligibility criteria

Qualifiers

Provision of signed and dated, written Informed Consent prior to any study specific proce-dures

Patient: males and females must be ≥ 70 years old

Patients who will undergo a TAVI procedure

Disqualifiers

- No obtained signed, dated and written Informed Consent.

Known thyroid dysfunction (for example: Basedow, Hashimoto,...)

Patients receiving any of the following: Lithium, Strumazol or a recent treatment of radio-Iode

Trial design

Treatments tested in this trial

  • Assesment of thyroïd function

Treatment groups

20 Participants
are divided into 1 treatment group