About this trial
The goal of this clinical trial is to investigate the effects of acute passive continuous hypoxemia (simulated high-altitude at rest) on appetite and energy intake in healthy young female adults. The main questions it aims to answer are:
* Does six hours of simulated high-altitude (5000 meters) reduce scores of subjective appetite and energy intake? * Do changes in appetite and energy intake persist in the hours following the end of hypoxic exposure? Researchers will compare the effects of simulated high-altitude to a control normoxia (sea-level) condition to see if exposure to low oxygen levels independently affect appetite and energy intake.
Participants will:
* Visit the laboratory for a preliminary screening session to assess eligibility. * Undergo two randomized, single-blind, experimental sessions consisting of six hours of passive exposure to normoxia or hypoxia in a climate-controlled chamber. * Consume foods provided from a curated list, served in ad libitum quantities, after leaving the laboratory to assess post-exposure energy intake.
Eligibility criteria
Qualifiers
English or French speaking
Ability to provide informed consent
Disqualifiers
History or evidence of chronic disease
Current use of hypolipemic medication
Current use of hormonal contraceptives
Current use of antidepressants
Trial design
Treatments tested in this trial
- Normoxia
- Hypoxia (simulated altitude of 5000 meters above sea-level)
Treatment groups
Sponsors and collaborators
University of Ottawa
Lead sponsor
Natural Sciences and Engineering Research Council, Canada
Collaborator
Hopital Montfort
Collaborator
Institut du Savoir Montfort
Collaborator