Hypoxia, Appetite, and Energy Intake in Young Female Adults

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-30
SponsorUniversity of Ottawa

About this trial

The goal of this clinical trial is to investigate the effects of acute passive continuous hypoxemia (simulated high-altitude at rest) on appetite and energy intake in healthy young female adults. The main questions it aims to answer are:

* Does six hours of simulated high-altitude (5000 meters) reduce scores of subjective appetite and energy intake? * Do changes in appetite and energy intake persist in the hours following the end of hypoxic exposure? Researchers will compare the effects of simulated high-altitude to a control normoxia (sea-level) condition to see if exposure to low oxygen levels independently affect appetite and energy intake.

Participants will:

* Visit the laboratory for a preliminary screening session to assess eligibility. * Undergo two randomized, single-blind, experimental sessions consisting of six hours of passive exposure to normoxia or hypoxia in a climate-controlled chamber. * Consume foods provided from a curated list, served in ad libitum quantities, after leaving the laboratory to assess post-exposure energy intake.

Eligibility criteria

Qualifiers

English or French speaking

Ability to provide informed consent

Disqualifiers

History or evidence of chronic disease

Current use of hypolipemic medication

Current use of hormonal contraceptives

Current use of antidepressants

Trial design

Treatments tested in this trial

  • Normoxia
  • Hypoxia (simulated altitude of 5000 meters above sea-level)

Treatment groups

10 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Ottawa

Lead sponsor

Natural Sciences and Engineering Research Council, Canada

Collaborator

Hopital Montfort

Collaborator

Institut du Savoir Montfort

Collaborator