iCAGES-guided Precision Therapy for Cancers in Contrast to Standard Care or IHC-guided Theray

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorSecond Affiliated Hospital of Guangzhou Medical University

About this trial

This study prospectively evaluates whether the use of iCAGES (integrated CAncer GEnome Score) tool in guiding the treatment of advanced cancers is superior to current standard care or IHC-guided therapy in progress free survival (PFS),overall survival (OS),and improvement of life quality.

Eligibility criteria

Qualifiers

Pathological and clinical diagnosis of recurrence / metastatic lung cancer or other advanced cancers.

There are PACS images available at the Second Affiliated Hospital of Guangzhou Medical University and the collaborated Hospitals.

The patient is informed consent and signed a written consent.

Disqualifiers

Age > 70 or <18 years old.

Previous history of malignant tumors.

Pregnant or lactating female patients.

Any serious concomitant disease that is expected to have an adverse effect on prognosis, including the heart disease that treatment is required, unsatisfactory controlled diabetes and psychiatric disorders.

Trial design

Treatments tested in this trial

  • inhibitors, ADC drugs such as tarceva, capmatinib, padcev et al for A/C group.

Treatment groups

250 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Second Affiliated Hospital of Guangzhou Medical University

Lead sponsor

The First Affiliated Hospital of Guangzhou Medical University

Collaborator

Sun Yat-sen University

Collaborator