About this trial
This study prospectively evaluates whether the use of iCAGES (integrated CAncer GEnome Score) tool in guiding the treatment of advanced cancers is superior to current standard care or IHC-guided therapy in progress free survival (PFS),overall survival (OS),and improvement of life quality.
Eligibility criteria
Qualifiers
Pathological and clinical diagnosis of recurrence / metastatic lung cancer or other advanced cancers.
There are PACS images available at the Second Affiliated Hospital of Guangzhou Medical University and the collaborated Hospitals.
The patient is informed consent and signed a written consent.
Disqualifiers
Age > 70 or <18 years old.
Previous history of malignant tumors.
Pregnant or lactating female patients.
Any serious concomitant disease that is expected to have an adverse effect on prognosis, including the heart disease that treatment is required, unsatisfactory controlled diabetes and psychiatric disorders.
Trial design
Treatments tested in this trial
- inhibitors, ADC drugs such as tarceva, capmatinib, padcev et al for A/C group.
Treatment groups
Sponsors and collaborators
Second Affiliated Hospital of Guangzhou Medical University
Lead sponsor
The First Affiliated Hospital of Guangzhou Medical University
Collaborator
Sun Yat-sen University
Collaborator