This multicenter, open-label, parallel-group, randomized controlled trial aims to compare the live birth rate, fertilization outcomes, other pregnancy outcomes and safety between ICSI and conventional IVF among couples with unexplained infertility in China.
Aged 20-38 years
18.5 < BMI < 24kg/m2
Regular menses or confirmed ovulation;
Normal ovarian reserve;
Preimplantation genetic testing (PGT) cycles
In vitro maturation (IVM) cycles
Using donor sperm/oocyte
Using frozen sperm/oocyte
Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead sponsor
Renmin Hospital of Wuhan University
Collaborator
Jiaxing Maternity and Child Health Care Hospital
Collaborator
Ningbo Women & Children's Hospital
Collaborator
Beijing Obstetrics and Gynecology Hospital
Collaborator
Xiangyang Central Hospital
Collaborator
Huangshi Central Hospital
Collaborator