About this trial
The objective of this study is to design and develop a gene chip for detecting pathogenic bacteria in diabetic foot infection wounds. This innovative gene chip technology enables rapid and accurate identification of pathogens at the site of infection by detecting the 16SrDNA sequence of pathogenic bacteria.
Diabetic foot infection is a common serious complication in diabetic patients, often accompanied by complex pathogenic bacteria population, and due to the variety of infection types, traditional pathogen detection methods are time-consuming and low accuracy, patients may miss the best treatment opportunity. Now commonly used genetic identification of pathogenic bacteria often find a variety of bacteria, resulting in the actual pathogenic bacteria difficult to judge.
Eligibility criteria
Qualifiers
Age ≥ 18 years old
Gender: males and females
Patients diagnosed with diabetic foot infection with an infected wound
It can provide sufficient infected wound samples (≥5mm³ infected wound tissue samples or ≥100μL infected wound secretions) and can be used for detection and analysis of gene chips
Disqualifiers
Patients with undiagnosed diabetic foot infection
Patients who had received antibiotics within 4 weeks prior to sampling
Complicated with serious systemic disease (e.g., malignant tumor, severe cardiopulmonary insufficiency, etc.)
Pregnant or lactating women
Trial design
Treatments tested in this trial
- The infected wound of the patient's foot ulcer was collected
Treatment groups
Sponsors and collaborators
Shanghai Jiao Tong University School of Medicine
Lead sponsor
Ruijin Hospital
Sponsor institution