About this trial
This study was a multicenter, retrospective cohort study. Although advancements in surgical techniques have mitigated the incidence of intestinal anastomotic fistula, complete avoidance remains elusive. Anastomotic leakage (AL) complications directly impinge on postoperative quality of life and pose life-threatening risks if inadequately managed. Given AL's adverse prognostic implications and the financial strain on patients' families, identifying its risk factors aids in perioperative risk assessment, enabling timely clinical decisions on interventions to enhance prognosis and curtail adverse outcomes and economic investments.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients with postoperative pathological diagnosis of primary ovarian, fallopian tube or peritoneal cancer
Patients undergoing tumour cytoreductive surgery combined with colorectal resection and stage I intestinal anastomosis
No history of other malignant tumours
Complete case data
Disqualifiers
Previous combination of malignant tumours of other organs
Comorbidities with serious diseases related to other organs
Patients undergoing secondary tumour cytoreduction
Trial population
All inpatients undergoing colorectal resection for patients with ovarian, fallopian tube and peritoneal cancer from January 2018 to June 2023 from multiple study centres were selected for the study.
Trial design
Cohort
Retrospective
Treatments tested in this trial
Type of bowel resection, surgical complexity score, intraoperative blood loss, perioperative erythrocyte transfusion, type of anastomosis
Procedure/SurgeryBasic information about ovarian cancer patients and factors associated with preoperative, intraoperative and postoperative periods
Treatment groups
Trial outcomes
Primary outcomes
Risk Factors and a Prediction Model for Postoperative Intestinal Anastomotic Leakage in Ovarian Cancer
Risk Factors
Sponsors and contacts
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