Identification of Risk Factors and Construction of Prediction Model for Postoperative Intestinal Anastomotic Leakage in Ovarian Cancer

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
AgeNot listed
SponsorZhongda Hospital

About this trial

This study was a multicenter, retrospective cohort study. Although advancements in surgical techniques have mitigated the incidence of intestinal anastomotic fistula, complete avoidance remains elusive. Anastomotic leakage (AL) complications directly impinge on postoperative quality of life and pose life-threatening risks if inadequately managed. Given AL's adverse prognostic implications and the financial strain on patients' families, identifying its risk factors aids in perioperative risk assessment, enabling timely clinical decisions on interventions to enhance prognosis and curtail adverse outcomes and economic investments.

Eligibility criteria

Qualifiers

Patients with postoperative pathological diagnosis of primary ovarian, fallopian tube or peritoneal cancer

Patients undergoing tumour cytoreductive surgery combined with colorectal resection and stage I intestinal anastomosis

No history of other malignant tumours

Complete case data

Disqualifiers

Previous combination of malignant tumours of other organs

Comorbidities with serious diseases related to other organs

Patients undergoing secondary tumour cytoreduction

Trial design

Treatments tested in this trial

  • Type of bowel resection, surgical complexity score, intraoperative blood loss, perioperative erythrocyte transfusion, type of anastomosis

Treatment groups

300 Participants
are divided into 2 treatment groups

Sponsors and collaborators