IFOC Compared With LIFT in High Anal Fistula

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCairo University

About this trial

Patients presenting to the outpatient clinic at Kasr Al-Ainy Hospitals with high anal fistula will be assessed according to the inclusion and exclusion criteria. The study purpose will be explained, and informed consent will be obtained from eligible participants. A detailed medical history and routine preoperative assessment will be conducted.

Clinical evaluation will include identification of the internal and external openings, assessment of discharge, and continence status using the Jorge-Wexner incontinence score. MRI fistulogram will be performed preoperatively to evaluate the fistula tract and its relation to the sphincter complex.

Patients will be randomly allocated into two equal groups (1:1 ratio) using a computer-generated sequence:

Group A: Undergo LIFT procedure Group B: Undergo IFOC procedure Both procedures will be performed as per standard surgical techniques. Postoperatively, patients will start oral fluids after 2 hours and resume a normal diet as tolerated. Discharge is planned on the first postoperative day unless otherwise indicated. Follow-up will be conducted at 1 week, 2 weeks, 1 month, and monthly thereafter for at least 6 months to assess healing and detect complications, including recurrence.

Eligibility criteria

Qualifiers

Patients with high anal fistula from both gender

Disqualifiers

Patient with preoperative fecal incontinence

Fistula secondary to colorectal malignancy

Patients with inflammatory bowel disease

Fistula secondary to trauma or radiation

Trial design

Treatments tested in this trial

  • Intra-anal Fistulotomy With Fistula Opening Closure (IFOC)
  • Ligation of the Intersphincteric Fistula Tract (LIFT)

Treatment groups

66 Participants
are divided into 2 treatment groups

Sponsors and collaborators