Imaging and Treatment Planning for Cardiac Radioablation

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorStewart Gaede

About this trial

Cardiac radioablation is a new treatment for ventricular tachycardia (VT), which uses beams of radiation to treat heart scar that causes VT. To identify the scar areas, magnetic resonance imaging (MRI) and computed tomography (CT) imaging are often used. These are both types of medical imaging that allow clinicians to examine scar area without having to do invasive surgery.

Researchers have developed new heart imaging protocols using both MRI and CT. Their MRI protocol method can now spot both dense and scattered scar tissue. The CT protocol combines multiple different types of scans into a single appointment and uses a special scanner that captures the motion of the heart. For this study, patients will undergo CT and MRI imaging according to these new imaging protocols.

With this study, researchers aim to show that these new imaging protocols can be undergone by patients with ventricular tachycardia and can be used to identify scar. Researchers will also use these scans to make radiation treatment plans to identify which types of treatment can be delivered safely to patients.

Eligibility criteria

Qualifiers

Ischemic cardiomyopathy with monomorphic VT

Referred by cardiologists

18 years of age or older

Disqualifiers

• Polymorphic ventricular tachycardia

Ventricular fibrillation

Pregnant or breastfeeding or planning to become pregnant or breastfeed during the study

Estimated glomerular filtration rate ≤ 30 mL/min/1.73m2

Trial design

Treatments tested in this trial

  • CT and MRI

Treatment groups

15 Participants
are divided into 1 treatment group

Sponsors and collaborators

Stewart Gaede

Lead sponsor

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sponsor institution