About this trial
Aim of this study is to improve patient care in Moyamoya Patients by improving Imaging technologies and aiming to identify factors involved in disease progression.
Main tasks are:
* Analysis of CO2-triggered BOLD fMRI for analysis of cerebral hemodynamics in comparison to H2 15O PET/CT * Analysis of longitudinal changes of contrast enhancement in vessel-wall imaging and correlation of disease activity with biosampling * Definition of a standardized recommendation for pre- and postoperative imaging of Moyamoya patients
Eligibility criteria
Qualifiers
Patients with suspicion of Moyamoya Disease
Patients able to understand the study and to give their informed consent
Disqualifiers
Cerebral vascular disease caused by atherosclerosis
Vasculitis
Contraindications to MRI
Contraindications to PET/CT
Trial design
Treatments tested in this trial
- MRI
- H2 15O PET/CT
- Biosampling
Treatment groups
Sponsors and collaborators
University Hospital Tuebingen
Lead sponsor
University Hospital Freiburg
Collaborator