Imaging Measures of Respiratory Health Registry
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age0-99
SponsorUniversity of British Columbia
About this trial
This is a prospective, observational cohort registry that aims to collect data on pulmonary structure and function in healthy people and those with respiratory disease, using structural and functional pulmonary 1H-MRI and hyperpolarized 129Xe-MRI.
Outcome measures generated from MRI may include but are not limited to measures of regional ventilation, pulmonary microarchitecture, and regional gas exchange. Additionally, one of the goals of the registry is to facilitate the development of novel image analysis techniques that have not yet been invented.
These data will be stored along with demographic data, clinical data, and pulmonary function testing (PFT) data.
This is an open registry. Eligible local and international investigators/institutions can apply for access.
Eligibility criteria
Qualifiers
Physician-diagnosed lung disease - based on a diagnosis made by a treating staff physician and confirmed by the principal investigator.
Age 0-99 years.
Informed consent by participant, parent, or legal guardian
In the opinion of the Investigator, the participant will likely be able to perform maneuvers to obtain technically acceptable pulmonary XeMRI images.
Disqualifiers
Physical findings at screening that, in the opinion of the Investigator, would compromise the safety of the participant or the quality of the research data.
Requirement of supplementary oxygen to maintain an oxygen saturation above 95%.
Failed MRI screening form.
History of claustrophobia.
Trial design
Treatments tested in this trial
- 1H and Xe-129 MRI
Treatment groups
1,000 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov