Imaging the Pathogenesis of Cerebral Small Vessel Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorJohns Hopkins University
About this trial
Cerebral small vessel disease (CSVD) can lead to vascular cognitive impairment and dementia (VCID). The hallmark of CSVD is the appearance and progression of white matter hyperintensities (WMH) on MRI. The goal of this study it to recruit and follow individuals at risk for WMH progression and use serial MRI scanning to gain insights into the pathogenesis of CSVD.
Eligibility criteria
Qualifiers
Clinical or radiographic evidence of ischemic stroke
One vascular risk factor (hypertension, hyperlipidemia, or diabetes)
Evidence of cerebral small vessel disease on MRI
Disqualifiers
Inability to complete 3 research MRI scans over 1.25 years
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Johns Hopkins University
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborator
Source ClinicalTrials.gov