Immune Homeostasis in Sepsis and Septic Shock

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCharles University, Czech Republic

About this trial

Detailed description of immune response and its dynamics in sepsis and septic shock patiens by means of transcriptomics, flow-cytometry and cytokine analysis.

Eligibility criteria

Qualifiers

sepsis/septic shock (SEPSIS-3)

age ≥18

informed consent

inclusion within first 24hrs after development/diagnosis of septic shock

Disqualifiers

disagreement of the patient or legal representative with the entry into the study

patients with primary or secondary immunodeficiency

presence of active haematological malignancy or an active non-haematological malignancy

Trial design

Treatments tested in this trial

  • transcriptomics
  • flow-cytometry
  • cytokines

Treatment groups

200 Participants
are divided into 3 treatment groups