Immunogenomic Analyses of Pediatric Catatonia
ConditionCatatonia
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age0-17
SponsorRady Pediatric Genomics & Systems Medicine Institute
About this trial
Rady Children's Institute for Genomic Medicine seeks to understand the genomes and immune systems in 40 children and adolescents who are admitted to Rady Children's Hospital San Diego with a catatonia diagnosis. Cutting-edge genome and protein sequencing technology will be used to better understand how immunological and genetic assessments may improve the ability to identify the cause of catatonia and impact care. The investigator also hopes to identify new genetic and/or autoimmune causes of catatonia that may inform new treatment for future patients.
Eligibility criteria
Qualifiers
Child/adolescent Ages 0-17 (2) with a diagnosis of catatonia.
Biological parents of child/adolescent enrolled in this study for the purposes of reflex testing. Family members are eligible for participation in this study if they are presumed to be genetically related to a patient participant
Disqualifiers
Already received any prior whole genome sequencing or exome sequencing.
Unable to approach the family or patient for enrollment.
Unable to obtain informed consent.
They are known to not be genetically related to the child/adolescent patient participant
Trial design
Treatments tested in this trial
- Genetic: Genomic sequencing and molecular diagnostic results, if any.
- Phage display ImmunoPrecipiation Sequencing (PhIP-Seq)
Treatment groups
120 Participants
are divided into 1 treatment groupLocations
Sponsors and collaborators
Rady Pediatric Genomics & Systems Medicine Institute
Lead sponsor
Brain & Behavior Research Foundation
Collaborator
Source ClinicalTrials.gov