Immunological Mechanisms of Rejection in Uterine Transplantation

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorHopital Foch

About this trial

The objective of this study is to understand the mechanisms of rejection in uterine transplantation and to search for non-invasive markers of rejection. The biological samples necessary for our research have been or will be collected during procedures (biopsies, smears, vaginal swab, blood tests) carried out as part of the scheduled follow-up of patients. These will be samples whose collection is minimally or not invasive

Eligibility criteria

Qualifiers

Patient going to or having received a uterine transplant OR Patient going to or having donated a uterus for a recipient included in the study OR Premenopausal woman to undergo gynecological surgery under general anesthesia: for 4 of them it was a hysterectomy and they must be under 45 years old, the other 6 must be under 38 years old.

Disqualifiers

Pregnancy in progress

Current infection

Cervical dysplasia

History of transplant or transfusion

Trial design

Treatments tested in this trial

  • Specimens

Treatment groups

30 Participants
are divided into 3 treatment groups

Sponsors and collaborators