Immunological Profile for Patients Treated With CAR-T Cells
ConditionHematologic Neoplasms
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorInstitut Paoli-Calmettes
About this trial
In the frame of Si-CART study, blood will be collected from patients treated with CAR-T cells: before (at Day (D)-6 and D0 before cells injection), post infusion at D3, D5,D7, D9, D11, D14, D18, D 21, Month (M) 2 and M12 post injection.
A cerebrospinal fluid sample will also be collected if a Cerebrospinal Fluid Analysis Lumbar puncture is performed
Eligibility criteria
Qualifiers
Age ≥ 18 years
Planned injection of CAR-T cells within the scope of marketing authorization
Signed informed consent
French social security affiliation
Disqualifiers
Pregnant women, or women of childbearing potential (without medically acceptable contraception) or breastfeeding women.
Patient in emergency situation, adult under legal protection (patient placed under tutorship, curatorship, or judicial protection) or unable to give his consent
Impossibility to comply with trial medical follow-up for geographic, social or psychological reasons
Trial design
Treatments tested in this trial
- Blood sample collection
Treatment groups
500 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov