Immunometabolic Mechanisms of Blood Flow Restriction (BFR) Training After Anterior Cruciate Ligament Reconstruction
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorYale University
About this trial
This is a crossover phase 4 study to evaluate the impact of blood flow restriction on immunometabolism and gene expression in immune cells in individuals undergoing rehabilitation from anterior cruciate ligament reconstruction.
Eligibility criteria
Qualifiers
Provision of signed and dated informed consent form
Stated willingness to comply with all study procedures and availability for two study visits at least 1 week apart
All genders, between 18 and 60 years of age
In good general health without any underlying medical conditions or prior injury that would place the subject at risk of further injury/illness by participating in the study
Disqualifiers
Serious medical conditions including cardiovascular, metabolic (diabetes), rheumatologic, pulmonary, or musculoskeletal.
Multiple ligament ruptures or trauma
Rheumatoid arthritis or other significant comorbidities
Lower extremity vascular pathology, including history of deep vein thrombosis
Trial design
Treatments tested in this trial
- AirBand
- uninflated AirBand
Treatment groups
20 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov