Immunonutrition for Improving the Efficacy of Immunotherapy in Patients With Metastatic Non-small Cell Lung Cancer

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorFondazione IRCCS Policlinico San Matteo di Pavia

About this trial

The present study was designed to evaluate the efficacy of the early systematic provision of oral nutritional supplements enriched in immunonutrients in non-small lung cancer patients undergoing immunotherapy and receiving nutritional counseling

Eligibility criteria

Qualifiers

Confirmed histological diagnosis of metastatic non-small cell lung cancer (both squamous and non-squamous histology);

First-line treatment with immunotherapy (alone or in combination with chemotherapy) for metastatic disease by investigators' choice within the framework of good clinical practice and in agreement with current guidelines;

Will to participate by providing written informed consent;

Availability to administer oral supplements and immunotherapy with or without chemotherapy;

Disqualifiers

Age < 18 years;

Inability to sign an informed consent;

Indication to or ongoing artificial nutrition support (totally compromised spontaneous food-intake) and incapacity or unavailability to consume oral nutritional supplements

Trial design

Treatments tested in this trial

  • Immunonutrition
  • Control dietary intervention

Treatment groups

180 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Fondazione IRCCS Policlinico San Matteo di Pavia

Lead sponsor

San Luigi Gonzaga Hospital

Collaborator

Azienda Ospedaliera Universitaria Integrata Verona

Collaborator

Humanitas Hospital, Italy

Collaborator