Immunopathological Analysis in a French National Cohort of Membranous Nephropathy

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Hospitalier Universitaire de Nice

About this trial

National cohort of all cases of membranous nephropathy (MN) during a 1 year period in France, based on a pathological and/or serological diagnostic, collecting the data on:

* incidence of MN * prevalence of anti-PLA2R1 and anti-THSD7A * clinical outcome one year after diagnosis or after relapse (complete remission, partial remission or persistent nephrotic syndrome) * environmental risk factors for the onset of MN * HLA markers * patient care status in France

Eligibility criteria

Qualifiers

Age 18 years or more

Biopsy on a native kidney consistent with MN and/or positivity for serum anti-PLA2R1 and/or anti-THSD7A antibodies

Signed informed consent

Disqualifiers

Diagnosis error based on the kidney biopsy staining or on serology analyses for the positivity for anti-PLA2R1 and/or anti-THSD7A

Patients unable to give an informed consent

Patients withdrawing an informed consent

Trial design

Treatments tested in this trial

  • Blood sample

Treatment groups

400 Participants
are divided into 1 treatment group