Glioblastoma (GBM) is the most common and most aggressive primary brain cancer in adults. GBM is more common in men than in women, with a male-to-female ratio of 1.6. Furthermore, being male is associated with a poorer prognosis. These data suggest that sex and/or sexual hormones and more specifically androgens may play a role in the initiation, the growth, and the resistance to treatments of GBM.
Patients aged ≥18 and ≤55
Newly diagnosed GBM
Surgery with complete or incomplete resection
Eligible for chemoradiotherapy
Active infection at the time of sampling or within the previous 14 days
Active immune disorders
Known patients with low-grade glioma that has undergone anaplastic transformation
Patients treated with corticosteroids