Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age5-13
SponsorUniversity of Colorado, Denver
About this trial
The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.
Eligibility criteria
Qualifiers
Children aged 5-13 years old
A history of cancer
Treatment with a chemotherapy regimen including VCR and/or DOX
Completion of chemotherapy at least one year prior to study enrollment and survey completion.
Disqualifiers
Primary pelvic tumor
Pelvic irradiation
Pre-existing bladder/bowel dysfunction
Spinal defects
Trial design
Treatments tested in this trial
- Non-invasive Urodynamic Test (niUDS)
- Urinary proteomic screen
- Dysfunctional Voiding Symptom Score Survey (DVSS)
Treatment groups
152 Participants
are divided into 4 treatment groupsSponsors and collaborators
University of Colorado, Denver
Lead sponsor
National Cancer Institute (NCI)
Collaborator
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
Children's Hospital Colorado
Collaborator
Source ClinicalTrials.gov