About this trial
Severe heart failure is a diagnosis with a very poor prognosis. Heart transplantation is the best treatment for terminal heart failure but this type of treatment is limited by the number of available organs. About 20-25% of possible donor hearts are not considered for transplantation because they have some form of functional impairment. The functional impairment affecting organ donors is, however, usually reversible. A number of retrospective studies show that cardiac function recovers and recipients of hearts with dysfunction do not have worse outcomes compared to recipients of hearts with perfect cardiac function. However, there are no prospective studies on whether the functional impairment of the donor heart is of significance for the recipient. With a systematic and simple investigation of the heart, it should be possible to identify the hearts that are safe to transplant. This will thus increase the number of available donors.
Eligibility criteria
Qualifiers
Patient who has been accepted for heart transplantation at the participating transplantation center
The research subject has given written consent to participate in the study
Aged 18 years or older
Disqualifiers
• Mental inability, reluctance or language difficulties that result in difficulty understanding the meaning of study participation
Another study, where the patient is included, which is not considered compatible with the current study.
Trial design
Treatments tested in this trial
- Heart transplantation 1
- Heart transplantation 2