Impact of Endometrial Compaction on Reproductive Outcomes After Cryotransfer of Euploid Embryos in a Natural Cycle

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-50
SponsorInstituto Bernabeu

About this trial

Multicenter prospective observational cohort study, comparing ongoing pregnancy rates in natural cycles for euploid embryo transfer in patients who present endometrial compaction at the time of the transfer versus those who have a stable or greater endometrial thickness with respect to the estrogenic phase.

Eligibility criteria

Qualifiers

Aged 18 to 50 years

Primary or secondary infertility

Normal uterine cavity

Endometrial preparation in a modified natural cycle for single embryo transfer

Disqualifiers

Uterine or endometrial disease (multiple myomatosis [>3 fibroids of > 3 cm], adenomyosis, Asherman syndrome)

Difficulties in correctly measuring endometrial thickness due to a retroverted or tilted uterus

History of recurrent implantation failure (3 or more transferred blastocysts of good quality, from their own oocyte [<35 years] or oocyte donation); recurrent early Pregnancy Loss (the loss of two or more pregnancies before 10 weeks of gestational age.

Suboptimal endometrial response (endometrium < 6 mm on the day of ovulation triggering).

Trial design

Treatments tested in this trial

  • Observational non intervention study

Treatment groups

206 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Instituto Bernabeu

Lead sponsor

Universidad Miguel Hernandez de Elche

Collaborator