About this trial
Multicenter prospective observational cohort study, comparing ongoing pregnancy rates in natural cycles for euploid embryo transfer in patients who present endometrial compaction at the time of the transfer versus those who have a stable or greater endometrial thickness with respect to the estrogenic phase.
Eligibility criteria
Qualifiers
Aged 18 to 50 years
Primary or secondary infertility
Normal uterine cavity
Endometrial preparation in a modified natural cycle for single embryo transfer
Disqualifiers
Uterine or endometrial disease (multiple myomatosis [>3 fibroids of > 3 cm], adenomyosis, Asherman syndrome)
Difficulties in correctly measuring endometrial thickness due to a retroverted or tilted uterus
History of recurrent implantation failure (3 or more transferred blastocysts of good quality, from their own oocyte [<35 years] or oocyte donation); recurrent early Pregnancy Loss (the loss of two or more pregnancies before 10 weeks of gestational age.
Suboptimal endometrial response (endometrium < 6 mm on the day of ovulation triggering).
Trial design
Treatments tested in this trial
- Observational non intervention study
Treatment groups
Sponsors and collaborators
Instituto Bernabeu
Lead sponsor
Universidad Miguel Hernandez de Elche
Collaborator