This project aims to study the effect of exercise in the obesity/overweight on the changes of physical fitness and blood components. This will provide novel knowledge for medical staffs, researchers, or companies developing alternative strategies for treating obesity/overweight, including drug development and health promotion project to delay or prevent the onset of the disease.
Male or female individuals aged between 25-45 years
Thai nationality
Ability to walk or perform daily activities independently, without the use of an assistive device
Body mass index (BMI) between 25-35 kg/m²
Smoking, substance abuse, or alcohol addiction
History of respiratory diseases, such as asthma, emphysema, or chronic obstructive pulmonary disease
History of cardiovascular diseases, such as coronary heart disease, aortic disease, arrhythmia, or deep vein thrombosis
History of high blood pressure (hypertension)
Single group
High-intensity interval training exercise on treadmill
DeviceHigh-intensity interval training exercise using 65% to 80% of heart rate max
Blood component assessment
Participant's blood components, e.g. extracellular vesicles, will be investigated by cell assays and proteomic analysis
Foot pressure distribution
Foot pressure distribution will be measured using a treadmill (Zebris FDM-T Treadmill System, zebris Medical GmbH, Germany)
Facial and abdominal fat thickness measurement
Facial and abdominal fat thickness and characteristics will be pictured and analyzed using ultrasound imaging
VO2max
VO2max parameter (ml/kg/min) will be examined using Cardio Pulmonary Exercise Test
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