Impact of HI-NPPV Vs LI-NPPV on Tolerance Among AECOPD Patients
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorBeijing Chao Yang Hospital
About this trial
To determine whether high-intensity NPPV, compared with low-intensity NPPV, could have an effect on the subjective tolerance in patients with an AECOPD and hypercapnia.
Eligibility criteria
Qualifiers
AECOPD confirmed by the 2019 criteria of the Global Initiative for Chronic Obstructive Lung Disease (GOLD);
Arterial pH <7.35 and PaCO2 >45 mmHg at screening entry;
PaCO2 >45 mmHg after a 6-hour trial of low-intensity NPPV.
Disqualifiers
Age <18 years
Excessive respiratory secretions with weak cough
Upper airway obstruction
Recent oral, facial, or cranial trauma or surgery
Trial design
Treatments tested in this trial
- High-intensity NPPV
- Low-intensity NPPV
Treatment groups
20 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov