Impact of Intraoperative Blood Pressure Components on Postoperative AKI: A Phenotype-Stratified Analysis

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorLanyue Zhu

About this trial

Postoperative acute kidney injury (AKI) is a serious complication often linked to low blood pressure during surgery. This study aims to better protect patients' kidneys by personalizing how blood pressure is managed during an operation.

The project has two main goals:

First, researchers will analyze data from over 44,000 past surgeries to identify which specific blood pressure measurements are the most critical warning signs for kidney damage.

Second, using this knowledge, they will build a smart tool (a machine learning model) to predict a unique, safe blood pressure target for each individual patient before their surgery begins.

This personalized approach is intended to give doctors a specific target to maintain during surgery, helping to prevent kidney injury and improve patient safety.

Eligibility criteria

Qualifiers

Patients undergoing non-cardiac surgery

Access to intraoperatively available invasive/noninvasive blood pressure monitoring data

Disqualifiers

Patients for Age < 18 yr

Patients without preoperative or postoperative creatinine records

Patients undergoing urinary surgeries

Patients with chronic kidney injury before surgery

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Sponsors and collaborators

Lanyue Zhu

Lead sponsor

Zhongda Hospital

Sponsor institution