ConditionsBreast CancerBreast Cancer SurvivorsAromatase InhibitorsOsteoporosis or OsteopeniaPilates Exercise
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age40-60
SponsorBenha University
About this trial
Breast cancer survivors receiving endocrine (hormonal) therapy (aromatase inhibitors) are at high risk for cancer treatment-induced bone loss and osteoporosis due to estrogen depletion.
Eligibility criteria
Qualifiers
Female breast cancer survivors aged 40-60 years.
Histologically confirmed stage I-III breast cancer.
Currently receiving hormonal therapy (aromatase inhibitors) for at least 3 months.
At risk of osteoporosis or with low bone mineral density (BMD) defined by T-score ≤ -1.0 at lumbar spine or hip.
Disqualifiers
Metastatic (stage IV) or recurrent breast cancer.
History of osteoporotic fractures in the past 12 months.
Severe cardiovascular, respiratory, or musculoskeletal conditions that contraindicate exercise.
Uncontrolled hypertension, diabetes, or thyroid disorders.
Trial design
Treatments tested in this trial
- Pilates Exercises
- Calcium and Vitamin D Supplementation
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov