Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSkidmore College
About this trial
The investigators long-term goal is to better understand novel interventions to promote cardiovascular health in humans. The goal of the proposed research is to investigate whether there is sex-specificity in the effects of dietary capsaicin on mechanisms regulating nitric oxide (NO) bioavailability, its effect on key markers of cardiovascular (CV) health, including BP, macro- and microvascular function, and arterial stiffness. This knowledge will provide critical insight into the effects of dietary capsaicin on CV health and will guide future trials.
Eligibility criteria
Qualifiers
relatively healthy (other than elevated blood pressure) non-smoking men and women over the age of 18 from the local community
Disqualifiers
Women who are without a period (not due to a birth control method, intrauterine device or menopause), are pregnant, attempting to conceive, or are breastfeeding will be excluded.
uncontrolled hypertension
Anyone with severe illness or compromised or suppressed immune system (e.g. taking immune suppressants, chronic viral infection or treatment).
Any participants with excessive sensitivity to spicy foods or fiber (psyllium husk) will be excluded
Trial design
Treatments tested in this trial
- Dietary capsules
Treatment groups
80 Participants
are divided into 2 treatment groupsSponsors and collaborators
Skidmore College
Lead sponsor
American Heart Association
Collaborator
Source ClinicalTrials.gov