Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality worldwide. Patients with peripheral arterial disease are at increased risk suffering from major adverse cardiac and limb events. Acute and chronic stress affect the cardiovascular system. Long-term negative stressors lead to cardiovascular diseases and can aggravate already existing cardiovascular diseases. However, current guidelines on cardiovascular disease prevention highlight stress as a cardiovascular risk factor there is a lack of consensus about the definition and measurement of stress. The aim of the proposed trial is to evaluate different stress measuring methods in patients with PAD depending on the occurrence of cardiovascular events.
Limb bypass surgery or
aorta-femoral bypass surgery or
percutaneous transluminal angioplasty revascularization of the iliac or infrainguinal arteries or
limb or foot amputation for arterial vascular disease or
atrial fibrillation
high premature ventricular contractions burden
pacemaker with constant ventricular pacing
antiarrhythmic drugs class I or III
University Hospital, Essen
Lead sponsor
Universität Duisburg-Essen
Collaborator