Impact of Thyroid Hormones on Human Glucose and Energy Metabolism
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorUniversity of Ulm
About this trial
The goal of this clinical trial to clarify the impact of changes in thyroid hormone levels on glucose and lipid metabolism.
Patients will be included in whom thyroid hormone levels are intentionally changed by treatment. In patients with Graves' disease, thyroid hormone levels will be lowered using medication, while in patients with thyroid cancer, thyroid hormone levels will be raised using medication. Oral glucose tolerance tests will be performed before treatment and at two time points after treatment begins to assess metabolic effects.
Eligibility criteria
Qualifiers
patients with initial diagnosis of graves disease OR
patients with initial diagnosis of thyroid carcinoma
Disqualifiers
contraindications for oral glucose tolerance test
Diabetes mellitus
Fasting glucose level ≥ 200 mg/dL
Exogenous insulin administration with action at the time of the test
Trial design
Treatments tested in this trial
- Oral Glucose Tolerance Test
Treatment groups
60 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov