This project aims to study the effects of different types of thyroid surgery and RAIT on ovarian function and pregnancy outcomes of DTC women of childbearing age, analyze possible risk factors, and assess whether potential risk factors such as age, thyroid stimulating hormone (TSH) levels and positive thyroid antibodies are related to ovarian hypofunction and adverse pregnancy outcomes.
Age 20-45 years old;
Premenopausal women whose thyroid B-ultrasound + surgical pathology is clearly differentiated thyroid cancer (papillar thyroid cancer or follicular thyroid cancer);
TNM stage is in stage I (T1-3, N0 or N1, M0);
Treatment of thyroid tumor resection: unilateral lobe of the thyroid + isthmus resection, total thyroidectomy, total thyroidectomy + RAIT.
Patients with malignant tumors in other parts or low undifferentiated thyroid cancer;
Patients with abnormal liver and kidney function;
TNM stage II and above;
History of ovarian surgery, hysterectomy, pelvic surgery or radiation therapy;