Impact of Vascular Resection on Survival and Postoperative Outcomes in Patients With Hilar Cholangiocarcinoma: A Retrospective Study

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorYongjun Chen

About this trial

Hilar cholangiocarcinoma is a highly aggressive malignancy, and surgical resection remains the only potentially curative treatment. Due to the frequent involvement of major vascular structures, vascular resection is increasingly performed to achieve negative surgical margins; however, its impact on survival and postoperative outcomes remains controversial. This retrospective study aims to evaluate the association between vascular resection and clinical outcomes, including survival and postoperative outcomes, in patients with hilar cholangiocarcinoma undergoing curative-intent surgery.

Eligibility criteria

Qualifiers

Patients who underwent surgical treatment at the Department of Hepatobiliary and Pancreatic Surgery of our hospital between January 2010 and December 2024, including those with or without concomitant vascular resection.

Pathologically confirmed diagnosis of hilar cholangiocarcinoma after surgery.

Complete clinical and follow-up data available for outcome analysis.

Disqualifiers

Patients with distant metastasis or who underwent only palliative or exploratory surgery.

Patients diagnosed preoperatively or intraoperatively with other types of biliary malignancies not located at the hilar region.

Patients with incomplete medical records or missing key clinical or follow-up data.

Trial design

Treatments tested in this trial

  • No Intervention: Observational Cohort

Treatment groups

300 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Yongjun Chen

Lead sponsor

Tongji Hospital

Sponsor institution