Impact of Yo-Yo Sleep on Cardiometabolic Health

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-49
SponsorColumbia University

About this trial

The goal of this clinical trial is to test the impact of repeated intermittent short sleep, with short sleep maintained 5 days per week followed by 2 days of prolonged sleep, compared to daily adequate sleep, on energy balance and cardiometabolic risk. A secondary goal of this research is to determine if maintaining a constant midpoint of sleep while undergoing intermittent short sleep, leads to better outcomes than intermittent short sleep with a 2-hour delay in sleep midpoint. The aims of this research will be tested in the context of a 3-group, parallel-arm, outpatient intervention of 4 weeks in duration, in young-to-middle-aged adults (aged 18-49 years).

Eligibility criteria

Qualifiers

Aged 18 to 49 years

BMI 20-29.9 kg/m2

Habitually sleeping 7-9 hours/night without sleep aids or naps

Disqualifiers

Sleep disorders

Psychiatric disorders (including eating disorders) and seasonal affective disorder

Pregnancy (current/prior year)

Breastfeeding

Trial design

Treatments tested in this trial

  • Intermittent Short Sleep (ISS)
  • Social Jetlag (SJL)
  • Sustained Adequate Sleep (SAS)

Treatment groups

72 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Columbia University

Lead sponsor

Icahn School of Medicine at Mount Sinai

Collaborator

University of Colorado, Denver

Collaborator

National Heart, Lung, and Blood Institute (NHLBI)

Collaborator