About this trial
The goal of this clinical trial is to test the impact of repeated intermittent short sleep, with short sleep maintained 5 days per week followed by 2 days of prolonged sleep, compared to daily adequate sleep, on energy balance and cardiometabolic risk. A secondary goal of this research is to determine if maintaining a constant midpoint of sleep while undergoing intermittent short sleep, leads to better outcomes than intermittent short sleep with a 2-hour delay in sleep midpoint. The aims of this research will be tested in the context of a 3-group, parallel-arm, outpatient intervention of 4 weeks in duration, in young-to-middle-aged adults (aged 18-49 years).
Eligibility criteria
Qualifiers
Aged 18 to 49 years
BMI 20-29.9 kg/m2
Habitually sleeping 7-9 hours/night without sleep aids or naps
Disqualifiers
Sleep disorders
Psychiatric disorders (including eating disorders) and seasonal affective disorder
Pregnancy (current/prior year)
Breastfeeding
Trial design
Treatments tested in this trial
- Intermittent Short Sleep (ISS)
- Social Jetlag (SJL)
- Sustained Adequate Sleep (SAS)
Treatment groups
Sponsors and collaborators
Columbia University
Lead sponsor
Icahn School of Medicine at Mount Sinai
Collaborator
University of Colorado, Denver
Collaborator
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator