Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients With MINOCA
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-85
SponsorInsel Gruppe AG, University Hospital Bern
About this trial
Myocardial infarction with non-obstructive coronary arteries (MINOCA) (i.e.\<50% stenoses) on coronary angiography) is an underappreciated clinical entity concerning 5-6% of patients with acute myocardial infarction. Approximately 50% of these patients remain without appropriate diagnosis and treatment.
The MINOCA study aims at systematically assessing the frequency of underlying pathologies of MINOCA and outcomes with a multidisciplinary etiologic work-up and follow-up of 5 years including, for the first time, an implantable cardiac monitor (ICM) to assess the frequency of atrial fibrillation as underlying cause for MINOCA.
Eligibility criteria
Qualifiers
≥18 years of age
Written informed consent
Acute myocardial infarction (AMI) type 1 in accordance with the 4th universal definition of myocardial infarction
Non-obstructive coronary arteries on angiography defined as the absence of coronary artery stenoses ≥50% in any potential infarct-related artery
Disqualifiers
Known atrial fibrillation or atrial flutter
History of atrial fibrillation or atrial flutter ablation
Known coronary artery disease
Previous MI
Trial design
Treatments tested in this trial
- CONFIRM Rx implantable cardiac rhythm monitor (Abbott)
- Systematic etiologic work-up for underlying causes of MINOCA
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Insel Gruppe AG, University Hospital Bern
Lead sponsor
University Hospital, Zürich
Collaborator
Bangerter-Rhyner Stiftung
Collaborator
Abbott
Collaborator
Source ClinicalTrials.gov