Improved Robotic-Assisted Radical Prostatectomy for Locally Advanced Prostate Cancer: Bladder Suspension and Preliminary Outcomes

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
AgeNot listed
SponsorFirst Affiliated Hospital of Fujian Medical University

About this trial

This study is a prospective, single-center clinical trial. It aims to establish an improved robotic-assisted radical prostatectomy for treating locally advanced prostate cancer. The technique evaluates the impact of preserving the anterior peritoneum of the bladder on postoperative bladder descent and urinary control recovery. A retrospective analysis compares this modified approach with traditional anterior approach surgery, assessing differences in oncological outcomes, early functional recovery, and postoperative complication rates. The goal is to provide new theoretical foundations and technical support for the prevention and treatment of postoperative urinary incontinence.

Eligibility criteria

Qualifiers

prostate biopsy and clinical confirmation of high-risk prostate cancer (PSA > 20 ng/mL, Gleason score ≥ 8, or cT stage ≥ T2c) followed by robotic-assisted radical prostatectomy

multiparametric MRI (mpMRI) with a 3.0 T scanner for prostate or pelvic scans performed within 30 days before the operation at our center

Eastern Cooperative Oncology Group (ECOG) performance status score between 0 and 1

Complete clinical and prostate biopsy pathological data.

Disqualifiers

Presence of surgical contraindications.

refusal of enhanced mpMRI imaging.

Trial design

Treatments tested in this trial

  • conventional Robotic-assisted radical prostatectomy group
  • Improved Robotic-assisted radical prostatectomy group

Treatment groups

300 Participants
are divided into 2 treatment groups