Improvement of Memory in Mild Cognitive Impairment
ConditionMild Cognitive Impairment
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age55-85
SponsorLucie Bréchet
About this trial
The Clinical Trial will systematically examine the feasibility of remote, caregiver-led tACS for older adults with memory deficits and evaluate whether repeated tACS leads to sustained improvement of neuronal activity and memory functions.
Eligibility criteria
Qualifiers
age ≥ 55 years old
clinical diagnosis of mild cognitive impairment (MCI) based on a comprehensive clinical assessment and standard neuropsychological examination including tests of language, visuospatial thinking, executive functions, and memory
confirmation of diagnosis will be made by Prof. Paul Unschuld, the study MD, based on a participant's cognitive evaluation and history
understanding of the informed consent
Disqualifiers
age < 55 years old
any current diagnosis of a psychiatric disorder (e.g., schizophrenia, bipolar disorder, depressive disorder)
other than MCI, any history of other progressive or genetic neurologic disorder (e.g., Parkinson's disease, multiple sclerosis, tubular sclerosis) or acquired neurological disease (e.g., stroke, traumatic brain injury, tumor), including intracranial lesions
history of head trauma resulting in prolonged loss of consciousness
Trial design
Treatments tested in this trial
- transcranial alternating current stimulation (tACS)
- high-density electroencephalography (hdEEG)
- Montreal Cognitive Assessment (MoCA)
Treatment groups
40 Participants
are divided into 3 treatment groupsSponsors and collaborators
Lucie Bréchet
Lead sponsor
University of Geneva, Switzerland
Sponsor institution
Source ClinicalTrials.gov