EUGENIE is a prospective multicentre interventional study, focused on improving endometrial cancer (EC) assessment by combining the new technique of genomic profiling with surgical extra uterine disease assessment. The investigators aim to correlate EC stage to each of the molecular subgroups of disease and thereby guide surgical treatment and staging of EC by determining the association between molecular classification and disease stage and evaluating if and how disease stage in each of the molecular subgroups associates with prognosis.
Voluntary written informed consent of the participant or their legally authorized representative has been obtained before any screening procedures
Women ≥ 18 years
First diagnosis of EC, all disease stages and all histo-types
Participant has a history of pelvic or para-aortic lymph node dissection or sampling, previous pelvic (and/or para-aortic) radiotherapy, previous neoadjuvant chemotherapy
Any disorder, which in the Investigator's opinion might jeopardise the participant's safety or compliance with the protocol
Any prior or concomitant treatment(s) that might jeopardise the participant's safety or that would compromise the integrity of the Study
University Hospital, Gasthuisberg
Lead sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Collaborator
University Medical Centre Maribor
Collaborator