Improving the Quality of Cryopreserved Ovarian Tissue Reimplantation Using Platelet-enriched Autologous Plasma

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
AgeNot listed
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna

About this trial

The study is aimed to evaluate the effects of intraovarian injection of autologous Platelet-enriched Autologous Plasma on the outcomes of orthotopic transplantation of cryopreserved ovarian tissue.

Eligibility criteria

Qualifiers

request for cryopreserved ovarian tissue transplantation;

premature ovarian failure or irregular mentrual cycles;

negative test for HIV, HBV, HCV, Treponema pallidum;

negative PAP test;

Disqualifiers

neoplastic contamination in cryopreserved ovarian tissue;

history of endometriosis;

endocrinological disorders present and not treated (uncompensated thyroid dysfunction, diabetes (type 1, type 2);

body mass index (BMI) >30 kg/m2;

Trial design

Treatments tested in this trial

  • Cryopreserved Ovarian Tissue Reimplantation

Treatment groups

45 Participants
are divided into 1 treatment group