Improving Tissue Repair After Injury in the Muscle-tendon Interface Muscle Tissue Injury
ConditionMuscle Injury
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-35
SponsorBispebjerg Hospital
About this trial
The study is a 2-week human study where 40 patients who are scheduled to undergo reconstructive knee surgery are randomized to administration of GH or placebo following or without neuromuscular electrical stimulation of hamstring muscles.The overall aim is to determine, the role of muscle connective tissue protein synthesis in muscle injury and repair.
Eligibility criteria
Qualifiers
Healthy men and women scheduled to undergo reconstructive knee surgery
BMI 18-35
Disqualifiers
Former or current use of growth hormone or anabolic steroids
Use of corticosteroids in the past 3 months
Use of any medication known to affect muscle or tendon turnover
Former participation in a study using deuterated water
Trial design
Treatments tested in this trial
- Electrical stimulation
- Growth hormone (somatropin)
- Control (No electrical stimulation, nor growth hormone)
Treatment groups
40 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov