About this trial
The general objective of this study is to compare in vitro and in vivo the hemodynamic performance of different types of aortic valve prostheses and possible surgical implantation techniques.
The study involves the collection of data deriving from tests and procedures foreseen by normal clinical practice, including a transthoracic color Doppler echocardiogram, to which is added a 4DFlow cardiac MRI (magnetic resonance imaging) without contrast medium, to be performed between 1 and 3 months after the operation.
The study will last 24 months and the patients involvement will end approximately 1-3 months after the intervention.
There are no direct benefits expected from participation in the study. However, the instrumental data obtained by echocardiogram and Magnetic Resonance Imaging will be useful for monitoring the medium-term surgical outcome of patients after surgery.
Eligibility criteria
Qualifiers
patients who underwent SAVR or TAVI for severe aortic stenosis
implanted with valve models and sizes among those which we evaluated in vitro
Disqualifiers
treated or untreated aortic root/ascending aorta aneurysm
preoperative aortic regurgitation more than moderate
recent (<12 weeks)/ concomitant revascularization
recent (<12 weeks) ACS
Trial design
Treatments tested in this trial
- MRI