A randomized controlled trial was conducted to compare the treatment efficacy of iRoot SP and nRoot SP Root Canal Sealer Materials in patients with chronic apical periodontitis.
Age ≥ 18 years.
Diagnosis of apical periodontitis conforming to the diagnostic criteria in Endodontics.
The affected tooth is deemed restorable upon evaluation, with non-vital pulp requiring extirpation.
The affected tooth is a single tooth with a fully developed apical foramen.
Patients with alveolar bone loss exceeding one-third of the root length.
Affected teeth with root fracture, root canal obstruction, calcification, or root surface caries.
Patients with severe systemic diseases (e.g., osteoporosis, mental disorders, hepatic or renal insufficiency).
Patients who have taken analgesics, immunosuppressants, or antibiotics within one week prior to enrollment.