Incidence of Major Complication in Case of Thoracic Aortic Aneurysm

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age45-80
SponsorUniversity Hospital, Lille

About this trial

Thoracic aneurysm is a silent disease with a potential mid-term high risk of death or major complications. Few data are available on the real incidence of major complications in case of small and moderate thoracic aneurysm. Different factors are supposed to increase the risk of aortic enlargement as high blood pressure and sleep disorder breathing. The modality of imaging and clinical follow-up are well defined. In this prospective observational study, the aim to assess the incidence of of major complications during follow-up in a population of patients with a small or moderate thoracic aneurysm. The study will also try to identify systemic factors influencing aneurysm evolution.

Eligibility criteria

Qualifiers

Documentation of an aortic root aneurysm > 40 mm

Agreement to participate to a longitudinal study and available for a 5 years follow-up

Disqualifiers

Presence of comorbidities or pathology with a prognosis of less than 1 year

Personal or family history of genetically documented elastic tissue disease or patient meeting the GAND clinical criteria suggestive of Marfan disease

High-grade mitra-aortic valve disease, even if asymptomatic

Unbalanced hypertension ≥ 180/110 mmHg

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Sponsors and collaborators

University Hospital, Lille

Lead sponsor

Santelys Association

Collaborator

Région Nord-Pas de Calais, France

Collaborator

Association de Cardiologie Nord-Pas de Calais

Collaborator