About this trial
This study aims to find out how often memory and thinking problems happen after surgery in people who already have memory issues before their operation. These memory problems are called postoperative cognitive decline (POCD). Older adults with memory problems before surgery may be more likely to have trouble with thinking, memory, and daily activities after their operation. This study will follow patients who already have memory problems before surgery and see how their thinking and memory change after surgery. The results will help doctors better understand how to care for these patients before, during, and after surgery.
Eligibility criteria
Qualifiers
Preexisting Cognitive Impairment (PreCI) Surgical Group
Age ≥ 60 years
Preoperative screening with MMSE and MoCA-B indicating mild cognitive impairment (MCI) or mild dementia
Undergoing elective non-cardiac surgery under general anesthesia
Disqualifiers
Expected difficulty in completing neuropsychological assessments (e.g., inability to communicate in Mandarin, blindness, or deafness)
Usual residence outside Shenzhen
Normative Reference Group
Age ≥ 60 years
Trial design
Treatments tested in this trial
- surgery
- norma