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Incidence of Residual Neuromuscular Blockade in Fraility in OncoGynae Surgery

ConditionsFrailtyNeuromuscular BlockadeGeneral Anesthetic Drug Adverse ReactionGynecologic CancerSurgical Complication
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorMahidol University

About this trial

Frailty among patients undergoing surgery is strongly associated with an elevated risk of adverse perioperative outcomes, heightened incidence of postoperative complications, increased mortality rates, and prolonged hospital length of stay. Our focus centers on investigating the frailty index in the context of complications experienced by patients undergoing oncologic gynecology surgery. The principal objective of this research is to elucidate the extent to which residual neuromuscular blocking agents are linked to frailty.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age >,= 18 years

Patients undergoing elective gynecologic-oncology surgery

Disqualifiers

Unable to communicate Thai

Unable to understand the questionnaire

Preexisting neuromuscular disease

Preexisting disease involved wrist that may affect the nerve stimulator examination

Trial design

Design model

Single group

Treatments tested in this trial

  • Train of four nerve stimulator

    Diagnostic test

    Patient receive nerve stimulation by TOF-scan equipment at recovery room after surgery.

Treatment groups

622 Participants
are divided into 1 treatment group
Group A: TOF nerve stimulationExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Incidence of residual neuromuscular blockade

Incidence of residual neuromuscular blockade with the relation of frailty after gynecologic oncology surgery

Time frame
0-30 minute after surgery
2

Incidence of frailty

Incidence of frailty in patients undergoing gynecologic oncology surgery

Time frame
0 - 24 hours preoperative

Secondary outcomes

1

Anesthetic technique used

Anesthetic technique used in patients undergoing gynecologic oncology surgery

Time frame
Throughout Intraoperative period, an average 3-5 hours
2

Rate of blood transfusion

Quantity of units blood transfusion

Time frame
Throughout Intraoperative period, an average 3-5 hours to 24 hours postoperative
3

Rate of vasopressor usage

Rate of vasopressor usage eg. ephedrine, norepinephrine

Time frame
Throughout Intraoperative period, an average 3-5 hours to 24 hours postoperative
4

Length of hospital stay

Total number of days of hospital stay

Time frame
Through study completion, an average of 1 year, an average 3 - 5 days

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Mahidol University

Lead sponsor

Source ClinicalTrials.gov
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