Increased Early Pain Relief by Adding Vertebroplasty to SBRT
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre hospitalier de l'Université de Montréal (CHUM)
About this trial
The goal of treating metastases is to preserve stability and neurological function while reducing pain. The actual standard of care is stereotaxic body radiation therapy (SBRT) alone in non-surgical patients. The added value of vertebroplasty to SBRT is not well documented in the literature, nor whether performing vertebroplasty before radiotherapy treatment leads to a reduction in the rate of fractures and post-SBRT pain.
Eligibility criteria
Qualifiers
Histological evidence of cancer.
Spinal and vertebral bone metastases (T5 to L5) documented by imaging.
Pain related to metastases ≥ 4 on a numerical scale 0-10.
Karnofsky performance index > 60 (ecog 0-2)
Disqualifiers
Pregnancy or breastfeeding.
Contraindications to MRI.
Histology: myeloma, lymphoma or plasmacytoma.
Radiotherapy prior to the level to be treated.
Trial design
Treatments tested in this trial
- Vertebroplasty
- Stereotactic Body Radiation Therapy only
Treatment groups
50 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov